biologics Archives | Jeremy M. Burnham, MD

Bone & Joint Clinic of Baton Rouge | Sports Medicine


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All Posts Tagged: biologics

Can Knee Injections Cure Knee Arthritis?

Knee arthritis and cartilage wear has traditionally been considered an uncurable condition. In fact, the only consistently successful treatment whas a total knee replacement. Although knee replacements are a good option for severe arthritis, they require a large surgery, a prolonged recorvery course, and are usually associated with temporary, but significant, postoperative pain. Fortunately, advances in medical knowledge and technology have produced some very promising non-surgical treatments for knee arthritis. While there may not be a cure for arthritis yet, many of these treatments have shown potential to delay the need for knee replacement surgery.

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PRP – Platelet Rich Plasma

Overview of PRP

Of all the orthobiologic treatments, PRP has turned out to be the early star in the sports medicine world. It is affordable, low-risk, and effective. Platelet Rich Plasma (PRP) is derived from one’s own blood, and contains a supraphysiologic concentration of platelets, healing enzymes, and growth factors. Although platelets are usually thought of in the context of the clotting process of blood, PRP contains many biologic elements which are crucial to healing (VEGF, FGF, IGF, PDGF, and TGF). In general, tendons and other soft tissues have a poor blood supply, and this can limit their ability to heal. An injection of concentrated PRP can provide healing growth factors to the injured area (imagine one month’s worth of healing nutrients in a single injection).

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